朱宝存

性别

男

出生年月

1979年5月

学历/学位

研究生/博士

职称（职务）

教授

研究领域

1. 光学探针的设计、合成及性能研究

2. 磁性荧光纳米传感器的构建及在环境毒性物质净化和定量分析中的应用

招生领域

环境工程，环境科学

学术与社会兼职

现作为Chemical Science、Analytical Chemistry、Environmental Science & Technology、Biosensors and Bioelectronics、Chemical Communications、ACS Applied Materials & Interfaces等杂志审稿人。

电子邮件

stu_zhubc@ujn.edu.cn OR lcyzbc@163.com

通讯地址

济南市市中区南辛庄西路336号必赢线路检测3003

个人简历

朱宝存，博士，教授，博士生导师。2010年7月毕业于北京理工大学，随后在必赢线路检测3003（原资源与环境学院）工作。

主要从事有机和有机-无机杂化的分子/纳米光学传感器研究。涉及用于生物重要物质检测的比色荧光分子探针和用于环境中有毒物质净化和监测的磁性荧光纳米传感器的设计、合成及其应用研究。作为第一作者或通讯作者在Analytical Chemistry、Chemical Communications、Biosensors and Bioelectronics、ACS Sensors、Sensors and Actuators B: Chemical、Chemical Engineering Journal、Analyst、Organic & Biomolecular Chemistry和Nanotechnology等国际期刊发表SCI论文60余篇，其中中科院一区论文27篇，论文被引用2000余次；单篇引用超过140次的研究性论文3篇，已授权国家发明专利10项。获得山东高等学校优秀科研成果二等奖（第一位，2012）、山东高等学校优秀科研成果三等奖（第一位，2014）各一项。

教学工作

主讲《仪器分析》、《化工原理》、《环境工程原理》等本科生课程；

主讲《现代环境分析测试技术》等研究生课程。

科研成果

功能性磁性荧光纳米传感器的制备及对水体中汞的净化和监测研究，国际领先 （2013.10，山东省教育厅）。

承担科研项目

（1）国家自然科学基金面上项目（No. 21777053），主持

（2）山东省重点研发计划项目（No. 2016GSF117010），主持

（3）山东省自然科学基金面上项目（No. ZR2017MB014），主持

（4）国家自然科学基金青年项目（No. 21107029），主持

（5）山东省优秀中青年科学家科研奖励基金（No. BS2013HZ007），主持

（6）中国博士后面上资助项目（No. 2013M541953），主持

发明专利

1. 快速高选择性硫化氢比色探针，专利号：201210512345.6

2. 无机汞/有机汞离子荧光探针的制备方法及应用，专利号：201510471108.3

3. 一种超灵敏分析汞离子的比色荧光探针及其制备方法，专利号：201611246359.2

4. 一种以硼酸频哪醇酯为识别受体的超灵敏高选择过氧化亚硝酸盐比色比率荧光探针，

专利号：201710218670.4

曾获荣誉

2013～2014年度获得437必赢会员中心“优秀教师”

2014～2016年连续三年获得437必赢会员中心“本科教学贡献奖”

2015～2016学年获得437必赢会员中心“优秀班主任”

第十五届“挑战杯”全国大学生课外学术科技作品三等奖（指导老师）

第三届山东省大学生科技创新大赛一等奖（指导老师）

第四届山东省大学生科技创新大赛二等奖（指导老师）

代表性科研论文

1. Baocun Zhu, Liu Wu, Meng Zhang, Yawei Wang, Ziyang Zhao, Zuokai Wang, Qingxia Duan, Pan Jia, Caiyun Liu. A fast-response, highly specific fluorescent probe for the detection of picomolar hypochlorous acid and its bioimaging applications. Sensors and Actuators B: Chemical, 2018, 263, 103-108. (IF = 6.393)

2. Baocun Zhu, Liu Wu, Yawei Wang, Meng Zhang, Ziyang Zhao, Caiyun Liu, Zuokai Wang, Qingxia Duan, Pan Jia. A highly selective and ultrasensitive ratiometric far-red fluorescent probe for imaging endogenous peroxynitrite in living cells. Sensors and Actuators B: Chemical, 2018, 259, 797-802. (IF = 6.393)

3. Baocun Zhu, Liu Wu, Meng Zhang, Yawei Wang, Caiyun Liu, Zuokai Wang, Qingxia Duan, Pan Jia. A highly specific and ultrasensitive near-infrared fluorescent probe for imaging basal hypochlorite in the mitochondria of living cells. Biosensors and Bioelectronics, 2018, 107, 218-223. (IF = 9.518)

4. Baocun Zhu, Ping Li, Wei Shu, Xin Wang, Caiyun Liu, Yue Wang, Zuokai Wang, Yawei Wang and Bo Tang*. Highly specific and ultrasensitive two-photon fluorescence imaging of native HOCl in lysosomes and tissues based on thiocarbamate derivatives. Analytical Chemistry, 2016, 88, 12532-12538. (IF = 6.35)

5. Baocun Zhu*, He Kan, Jingkai Liu, Hanqing Liu, Qin Wei and Bin Du. A highly selective ratiometric visual and red-emitting fluorescent dual-channel probe for imaging fluoride anions in living cells. Biosensors and Bioelectronics, 2014, 52, 298-303. (IF = 9.518)

6. Baocun Zhu*, Bingpeng Guo,Yunzhou Zhao, Bing Zhang and Bin Du. A highly sensitive ratiometric fluorescent probe with a large emission shift for imaging endogenous cysteine in living cells. Biosensors and Bioelectronics, 2014, 55, 72-75. (IF = 9.518)

7. Baocun Zhu, Fang Yuan, Rongxia Li, Yamin Li, Qin Wei, Zhenmin Ma,* Bin Du* and Xiaoling Zhang*. A highly selective colorimetric and ratiometric fluorescent chemodosimeter for imaging fluoride ions in living cells. Chemical Communications, 2011, 47, 7098-7100. (IF = 6.164，编辑专门刊文评论文章，已被引用143次)

8. Baocun Zhu, Chenchen Gao, Yunzhou Zhao, Caiyun Liu, Yamin Li, Qin Wei, Zhenmin Ma, Bin Du* and Xiaoling Zhang*. A 4-hydroxynaphthalimide-derived ratiometric fluorescent chemodosimeter for imaging palladium in living cells. Chemical Communications, 2011, 47, 8656-8658. (IF = 6.164，已被引用187次)

9. Baocun Zhu, Xiaoling Zhang,* Yamin Li, Pengfei Wang,* Hongyan Zhang and Xiaoqing Zhuang. A colorimetric and ratiometric fluorescent probe for thiols and its bioimaging applications. Chemical Communications, 2010, 46, 5710-5712. (IF = 6.164，已被引用173次)

10. Baocun Zhu*, Jie Zhao, Haiqin Yu, Liangguo Yan, Qin Wei and Bin Du*. Naphthalimide-functionalized Fe₃O₄@SiO₂ core/shell nanoparticles for selective and sensitive adsorption and detection of Hg²⁺. Chemical Engineering Journal, 2013, 219, 411-418. (IF = 8.355)

11. Caiyun Liu, Huifang Wu, Zuokai Wang, Changxiang Shao, Baocun Zhu* and Xiaoling Zhang*. A fast-response, highly sensitive and selective fluorescent probe for the ratiometric imaging of hydrogen peroxide with a 100 nm red-shifted emission. Chemical Communications, 2014, 50, 6013-6016. (IF = 6.164)

12. Yang Jiao, Baocun Zhu, Jihua Chen, Xiaohong Duan. Fluorescent sensing of fluoride in cellular system. Theranostics, 2015, 5, 173-187. (IF = 8.063)

13. Baocun Zhu*, Houlin Jiang, Bingpeng Guo, Changxiang Shao, Huifang Wu, Bin Du and Qin Wei*. A highly selective ratiometric fluorescent probe for hydrogen peroxide displaying a large emission shift. Sensors and Actuators B: Chemical, 2013, 186, 681-686. (IF = 6.393)

14. Baocun Zhu*, Weizhang Wang, Lunying Liu, Houlin Jiang, Bin Du and Qin Wei. A highly selective colorimetric and long-wavelength fluorescent probe for Hg²⁺. Sensors and Actuators B: Chemical, 2014, 191, 605-611. (IF = 6.393)

15. Baocun Zhu*, Peilun Yang, Haiqin Yu, Liangguo Yan, Qin Wei and Bin Du*. Development of a novel water-soluble magnetic fluorescent nanoparticle for selective detection and removal of Cu²⁺. Nanotechnology, 2013, 24, 495502. (IF = 3.399)

教学著作